Antineoplastic Activity of Extracts of the Antarctic Yeast Sporobolomyces roseus AL103 on Urinary Bladder Cancer Cells
نویسندگان
چکیده
Currently, malignant diseases are one of the leading causes mortality worldwide. Antarctic yeasts represent a poorly explored source novel bioactive compounds with antineoplastic activity and expected favourable toxicological profile. The aim work was evaluation antiproliferative proapoptotic potential extracts obtained from psychrophilic strain Sporobolomyces roseus AL103. Data MTT dye reduction assay showed that urothelial cancer cell line T-24 more sensitive (85--101 μg/mL) than non-tumour (CCL-1- 343 to 432 μg/mL). Apoptosis analysis after treatment different yeast revealed strong inhibit various antiapoptotic factors as well selective induction apoptosis in tumour cells confirmed by flow cytometry, too.
منابع مشابه
comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
15 صفحه اولthe effect of taftan pozzolan on the compressive strength of concrete in the environmental conditions of oman sea (chabahar port)
cement is an essential ingredient in the concrete buildings. for production of cement considerable amount of fossil fuel and electrical energy is consumed. on the other hand for generating one tone of portland cement, nearly one ton of carbon dioxide is released. it shows that 7 percent of the total released carbon dioxide in the world relates to the cement industry. considering ecological issu...
PHEOCHROMOCYTOMA OF THE URINARY BLADDER
One of the rarest tumors involving the urinary bladder is the pheochromocytoma. A case of pheochromocytoma of the urinary bladder in a young female suffering from headache and cystitis for many years is reported. Twenty-four hour urine VMA was normal. The patient was never hypertensive except during surgical manipulation of the tumor. Biopsy of the bladder resulted in massive hemorrhage.
متن کاملthe effect of explicit teaching of metacognitive vocabulary learning strategies on recall and retention of idioms
چکیده ندارد.
15 صفحه اولthe washback effect of discretepoint vs. integrative tests on the retention of content in knowledge tests
در این پایان نامه تاثیر دو نوع تست جزیی نگر و کلی نگر بر به یادسپاری محتوا ارزیابی شده که نتایج نشان دهندهکارایی تستهای کلی نگر بیشتر از سایر آزمونها است
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Dokladi na B?lgarskata akademiâ na naukite
سال: 2023
ISSN: ['2367-5535', '1310-1331']
DOI: https://doi.org/10.7546/crabs.2023.05.14